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Related Experiment Videos

Human pulp response after an adhesive system application in deep cavities.

J Hebling1, E M Giro, C A Costa

  • 1University of Michigan School of Dentistry, Ann Arbor 48103, USA.

Journal of Dentistry
|October 21, 1999
PubMed
Summary

The All Bond 2 adhesive system demonstrates acceptable biocompatibility in deep cavities. However, the pulpo-dentin complex response intensity is directly related to the remaining dentin thickness.

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Area of Science:

  • Dental Materials Science
  • Restorative Dentistry
  • Pulp Biology

Background:

  • Deep cavities pose challenges for restorative procedures due to proximity to the pulp.
  • Dentin adhesives are crucial for bonding restorative materials but can elicit pulpal responses.
  • Understanding the pulpo-dentin complex response to adhesives is vital for clinical success.

Purpose of the Study:

  • To evaluate the pulpo-dentin complex response to a dentin adhesive in deep human tooth cavities.
  • To compare the effects of direct adhesive application versus protection with calcium hydroxide cement.
  • To assess the impact of bacterial contamination on the pulpal response.

Main Methods:

  • Deep Class V cavities were prepared in human premolars.
  • Groups received direct dentin adhesive (DA), protected dentin (CH), or direct adhesive with plaque contamination (DAC).

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  • Histological analysis was performed at 7, 30, and 60 days post-restoration.

    • Main Results:

    • Groups DA and DAC exhibited more pronounced inflammatory responses than group CH.
    • Pulp reaction intensity correlated inversely with remaining dentin thickness.
    • No significant difference in inflammatory response was observed between direct adhesive application (DA) and contaminated direct adhesive (DAC).

    Conclusions:

    • The All Bond 2 adhesive system shows acceptable biocompatibility in deep cavities under the tested conditions.
    • Remaining dentin thickness is a critical factor influencing the pulpo-dentin complex's response to adhesive application.
    • Protecting dentin with calcium hydroxide cement reduced the inflammatory pulpal response.