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Evaluation of the cytocompatibility of three endodontic materials
M Guigand1, P Pellen-Mussi, A Le Goff
1Department of Endodontics, Faculty of Dentistry, University of Rennes, France.
Journal of Endodontics
|October 26, 1999
Abstract:
The goal of this in vitro study was to evaluate the relative cytocompatibility of three endodontic materials: calcium hydroxide, a calcium oxide-based compound, and a zinc oxide-eugenol-based sealer. The evaluation was conducted 24, 72, and 168 h after contact with the compounds and involved three complementary techniques: a colorimetric cytotoxicity test, scanning electron microscopy, and flow cytometry. The results we obtained confirmed the initial cytotoxicity of the zinc oxide-eugenol-based sealer and showed that the calcium oxide-based compound had the same relative cytocompatibility as calcium hydroxide.