Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

A young man with recurrent syncopes, right bundle branch block and ST segment elevation.

D Vanpee¹, D Blommaert, J B Gillet

¹Department of Emergency Medicine, Catholic University of Louvain, Mont-Godinne Hospital, Yvoir, Belgium.

The American Journal of Emergency Medicine

|October 26, 1999

Summary

This case study highlights Brugada syndrome, a rare condition causing sudden fainting due to ventricular arrhythmias. Early diagnosis is crucial to prevent potentially fatal cardiac events.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Epigenetic modifications of VEGF, cerebral hypoxia, and impaired cerebrovascular autoregulation as early indicators for preterm brain injury.

Function (Oxford, England)·2026

Same author

First results about ProAKAP4 concentration in stallion semen after cryopreservation in two different freezing media.

Cryobiology·2021

Same author

Expression, localization, and concentration of A-kinase anchor protein 4 (AKAP4) and its precursor (proAKAP4) in equine semen: Promising marker correlated to the total and progressive motility in thawed spermatozoa.

Theriogenology·2019

Same author

Arterial hypertension in patients with atrial fibrillation in Europe: A report from the EURObservational Research Programme pilot survey on atrial fibrillation.

International journal of cardiology·2018

Same author

[Minocycline-induced hyperpigmentation: not uncommon, but nonetheless important to recognise].

Nederlands tijdschrift voor geneeskunde·2016

Same author

A determination of the current causes of hyperkalaemia and whether they have changed over the past 25 years.

Acta clinica Belgica·2014

Area of Science:

Cardiology
Genetics
Electrophysiology

Background:

Brugada syndrome is a rare genetic disorder characterized by abnormal heart rhythms.
It can lead to syncope and sudden cardiac death, often in young, otherwise healthy individuals.
Diagnosis can be challenging due to its variable presentation and lack of structural heart abnormalities.

Observation:

A 33-year-old male presented with recurrent, sudden syncopes.
Electrocardiogram (ECG) revealed a right bundle branch block and ST segment elevation in leads V1-V2.
Extensive workup, including cardiac imaging and biopsies, ruled out ischemia, electrolyte imbalances, toxic exposure, and structural heart disease.

Findings:

The patient's ECG findings were consistent with Brugada syndrome.

Related Experiment Videos

Sustained monomorphic ventricular tachycardias were identified as the cause of syncope.

This diagnosis was made despite the absence of identifiable underlying cardiac pathology.

Implications:

Brugada syndrome requires prompt recognition and management to mitigate risks.
Delayed diagnosis can lead to life-threatening ventricular arrhythmias and sudden cardiac death.
Increased awareness and diagnostic vigilance are essential for affected patients.