Peritoneal membrane transport for low molecular weight substances with the use of one bag dialysate collection

The 24-hour collection of dialysate provides an accurate method for evaluation of both adequacy of dialysis and peritoneal membrane transport characteristics in patients on chronic ambulatory peritoneal dialysis. However, this test requires 24 hours to complete and therefore it is inconvenient for both patients and nurses in the every day practice. We determined the peritoneal membrane transport characteristics for low molecular weight substances of ten patients by using the dialysate collection of only one bag. Dialysate/plasma creatinine ratios were calculated for each of the 4 bags (DATT1, DATT2, DATT3, DATT4) as well as for the 24 hour dialysate (DATTo). We found a very good correlation between DATTo and the four DATTs. We therefore propose that the evaluation of the peritoneal membrane transport, at least for creatinine could be determined with the use of one bag dialysate collection.