Related Experiment Videos
[Methods of autologous peripheral blood stem cell (PBSC) mobilization in oncological and hematological patients]
L M Fregatova1, S A Shavva, G G Platonova
1Acad. I.P. Pavlov State Medical University, St. Petersburg.
Voprosy Onkologii
|October 26, 1999
Abstract:
The potential of peripheral blood stem cell (PBSC) mobilization with granulocyte (G-CSF) and granulocyte-macrophage (GM-CSF) colony-stimulating factors of chemotherapy has been assessed in patients with tumor or hematological disease. The study was intended to aid PBSC transplantation. It was shown that G-CSF administration increased the number of leukocytes in leukemia patients dramatically while mononuclear cell and colony-forming unit levels in G-CSF-mobilised PBSC were significantly higher than those collected with GM-CSF or chemotherapy.