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Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
Progressive perinatal bowel obstruction--a rare cause of short-bowel syndrome
C Sleeboom1, C M Kneepkens, S Ekkelkamp
1Pediatric Surgical Centre Amsterdam, University Hospital Vrije Universiteit, The Netherlands.
Abstract:
A girl was born after an uneventful pregnancy of 36 weeks. Prenatally, distended bowel loops had been seen on ultrasound. Multiple small-bowel atresia was diagnosed and treated surgically. In the course of the next eleven weeks, previously patent segments of small bowel became obstructed. In 4 separate operative sessions, several segments of jejunum and ileum were resected, leaving 23 cm of ileum with the ileocecal valve in place. On microscopic examination of all resected material, necrosis of the mucosa was found consistent with ischemia. The child survived and tolerated full enteral feeding at the age of 8.5 months. The origin of the progressive obliterating process remains unknown.
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