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Updated: Oct 6, 2026

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
Biphasic truncated exponential waveform defibrillation
1Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA. white.roger@mayo.edu
Abstract:
This paper presents data from studies that have compared the efficacies of biphasic truncated exponential (BTE) and monophasic damped sine (MDS) waveform defibrillation in patients with out-of-hospital cardiac arrest and in in-hospital defibrillation. When a shock is delivered, rhythms evolve rapidly in a variety of directions and take different courses, even over a short time. When defibrillation is defined as termination of ventricular fibrillation at 5 seconds postshock, whether to an organized rhythm or asystole, low-energy BTE shocks appear to be more effective than high-energy MDS shocks in out-of-hospital arrest. For future research, the terms associated with defibrillation should be standardized and used uniformly by all investi-gators. In particular, there should be an agreed-upon definition of shock efficacy.
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