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Raynaud's phenomenon in hypothyroidism.

B P Shagan, S A Friedman

    Angiology
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Hypothyroidism can cause Raynaud's phenomenon, a condition affecting blood vessels. Thyroid hormone replacement therapy effectively resolved symptoms in two patients, suggesting a link between autonomic function and this condition.

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    Area of Science:

    • Endocrinology
    • Vascular Medicine
    • Autonomic Neuroscience

    Background:

    • Raynaud's phenomenon is characterized by exaggerated vasoconstriction of peripheral blood vessels.
    • The underlying pathophysiology often involves altered autonomic nervous system function.
    • Hypothyroidism, a condition of insufficient thyroid hormone production, can impact various bodily systems.

    Observation:

    • Two patients presenting with Raynaud's phenomenon were diagnosed with concurrent hypothyroidism.
    • Symptoms of Raynaud's phenomenon in these patients resolved following the initiation of thyroid hormone replacement therapy.

    Findings:

    • Thyroid replacement therapy led to the disappearance of Raynaud's phenomenon symptoms.
    • Vascular reactivity studies in one patient indicated a reduction in vasomotor tone post-therapy.

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  • These findings suggest a potential role for hypothyroidism in the manifestation of Raynaud's phenomenon.

    • Implications:

    • Altered autonomic function in hypothyroidism may contribute to the development of Raynaud's phenomenon.
    • Screening for hypothyroidism may be beneficial in patients with Raynaud's phenomenon.
    • Thyroid hormone replacement could be a therapeutic strategy for Raynaud's phenomenon associated with hypothyroidism.