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Acute infantile hemorrhagic oedema
T Millard1, A Harris, D MacDonald
1Institute of Dermatology, St Thomas' Hospital, London, England. t.millard@umds.ac.uk
Journal of the American Academy of Dermatology
|October 27, 1999
Summary
Acute infantile hemorrhagic edema (AIHO) is a rare condition often mistaken for Henoch Schonlein Purpura (HSP). This case highlights AIHO as a distinct, benign form of cutaneous small vessel vasculitis.
Area of Science:
- Pediatrics
- Dermatology
- Rheumatology
Background:
- Acute infantile hemorrhagic edema (AIHO) is a rare vasculitis, first described in 1913.
- AIHO is frequently reported in European literature but less recognized in English-language publications.
- It shares similarities in cause and histopathology with Henoch Schonlein Purpura (HSP).
Observation:
- This case report focuses on a child diagnosed with AIHO.
- The condition presents with characteristic clinical and histopathological features.
- Key diagnostic criteria and differential diagnoses are considered.
Findings:
- AIHO is often considered a variant of HSP due to overlapping features.
- A notable distinction is the frequent absence of IgA, commonly found in HSP.
- AIHO is characterized by its benign and self-limiting nature.
Implications:
- Recognizing AIHO as distinct from HSP is crucial for accurate diagnosis and management.
- Emphasizing the benign prognosis of AIHO can alleviate parental concerns.
- Further research may clarify the classification of AIHO within cutaneous small vessel vasculitis (CSVV).