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Updated: Aug 11, 2026

Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
Published on: June 18, 2013
[Metabolism of mevalonate in human placenta]
1Katedry i Zakładu Chemii Ogólnej, Akademii Medycznej w Gdańsku.
Prenylation of protein rather than cholesterol synthesis, seems to be main "metabolic target" of mevalonate metabolism in the human placenta. It seems very probable that cytological transformation of cytotrophoblast cells to syncytiotrophoblast which occur during placental development, "switched off" activity of mevalonate biosynthesis in term placenta.
Prenylation of protein rather than cholesterol synthesis, seems to be main "metabolic target" of mevalonate metabolism in the human placenta. It seems very probable that cytological transformation of cytotrophoblast cells to syncytiotrophoblast which occur during placental development, "switched off" activity of mevalonate biosynthesis in term placenta.

