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Related Experiment Videos

The aortic valve with two leaflets--a study in 2,000 autopsies.

H M Pauperio1, A C Azevedo, C S Ferreira

  • 1Division of Paediatric Cardiology, Socor and Felicio Rocho Hospital, Belo Horizonte MG, Brazil. pauperio@globalsite.com.br

Cardiology in the Young
|October 27, 1999
PubMed
Summary

Bifoliate aortic valves, a common congenital heart anomaly, were found in 0.65% of 2,000 cadavers, primarily affecting white males and often leading to stenosis later in life.

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Area of Science:

  • Cardiovascular Anatomy
  • Congenital Heart Anomalies

Background:

  • The aortic valve typically has three leaflets.
  • Bifoliate aortic valves are a known congenital anomaly, but their prevalence and clinical implications require further investigation.

Purpose of the Study:

  • To determine the prevalence of bifoliate aortic valves in a Brazilian population.
  • To describe the morphological characteristics and associated pathologies of bifoliate aortic valves.

Main Methods:

  • Examination of 2,000 aortic valves from fresh cadavers (1,499 males, 501 females).
  • Detailed analysis of valve morphology, including leaflets, raphe, and signs of calcification.
  • Correlation of findings with demographic data and clinical history.

Main Results:

Related Experiment Videos

  • A prevalence of 0.65% (13 cases) for bifoliate aortic valves was observed, lower than previously reported.
  • All identified bifoliate valves were from males, predominantly white.
  • Most bifoliate valves showed thickening and calcification after the fourth decade, with stenosis being the most common complication.

Conclusions:

  • Bifoliate aortic valve is a common cardiac anomaly, with a lower prevalence in the studied Brazilian population.
  • The condition predominantly affects white males and is associated with age-related complications like stenosis.
  • While often isolated, associated conditions like endocarditis and aortic coarctation can occur.