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Updated: Aug 10, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
[Psychopathology-like states after craniocerebral trauma]
Abstract:
The presence of stable personal disharmony in the form of a reduced organic mental syndrome served as a criterion for diagnosis of personality changes after traumatic head injuries. The patients were divided into a group with prevalence of personality changes (81 patients) and a group with predominance of pronounced organic mental syndrome (141 patients). Personality disorders prevailed in the patients who had got mild and moderate traumas at the age of 13-25 years, with less number of additional pathogenic factors of exogenic organic spectrum in anamnesis. 3 variants of the course of personality disorders were recognized: with a tendency toward reduction of emotional and drive pathology; with a tendency to intensification of intellectual and mnestic disorders and transformation into large-scale organic mental syndrome; with a tendency toward an increase of pathological traits of personality in conditions of growing influence of the environmental and psychogenic factors.
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