Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Folic acid].

A Maekawa1, H Nakajima, T Kawata

  • 1Department of Applied Biology and Chemistry, Tokyo University of Agriculture.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 14, 1999
PubMed
Summary

Folic acid (folate) is crucial for DNA synthesis and cell replication. Low folate intake during pregnancy can cause neural tube defects, and deficiency is linked to heart disease and vascular issues.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Communication with Peritoneal Dialysis Patients Post-Kumamoto Earthquake.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2017
Same author

Identification and analysis of CXCR4-positive synovial sarcoma-initiating cells.

Oncogene·2015
Same author

Esophagogastric junctional adenocarcinoma originating from endoscopically unrecognizable Barrett's epithelium.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2015
Same author

Preferable sites and orientations of transgene inserted in the adenovirus vector genome: The E3 site may be unfavorable for transgene position.

Gene therapy·2015
Same author

Category analysis of the substituted anilines studied in a 28-day repeat-dose toxicity test conducted on rats: correlation between toxicity and chemical structure.

SAR and QSAR in environmental research·2008
Same author

[Surgical repair of traumatic rupture of the discending aorta through 'L'-thoracotomy].

Kyobu geka. The Japanese journal of thoracic surgery·2007

Area of Science:

  • Biochemistry
  • Cell Biology
  • Nutritional Science

Context:

  • One-carbon metabolism is vital for cellular processes.
  • Tetrahydrofolate derivatives are essential coenzymes.
  • Folic acid is a key B vitamin.

Purpose:

  • To highlight the critical roles of folic acid in biological systems.
  • To underscore the health implications of folate deficiency.

Summary:

  • Folate derivatives (tetrahydrofolate) are central to DNA synthesis and cell replication.
  • Folic acid deficiency is linked to pernicious anemia.
  • Inadequate folate intake during pregnancy is associated with neural tube defects like spina bifida.
  • Low plasma folate levels correlate with increased risk of cardiovascular and cerebrovascular diseases in hyperhomocysteinemia.

Impact:

  • Recognizes the significant nutritional importance of folate.
  • Emphasizes folate's role in preventing birth defects.
  • Highlights folate's impact on cardiovascular health.