Related Experiment Video
Updated: Jul 23, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 4, 2015
[Effects of chronic radiation exposure on erythrocyte metabolism and functioning]
N N Velikiĭ1, L S Starikovich, V N Korobov
1Iv. Franko Lvov State University, Ukraine. veliky@biochem.lviv.UA
Abstract:
The structural and functional state of blood erythrocytes in people exposed to radiation during Chernobyl NPP accident was studied two or six years later. The changes in oxygen transport system of erythrocytes and in the ratio between some organic phosphate fractions were observed. The beta-carotene per os administration to rats during low-level irradiation increased hemolytic stability and activity of glycolytic enzymes, that bears witness to the increasing of organism adaptive reactions at provitamin administration during irradiation.
More Related Videos
Related Concept Videos
Biological Effects of Radiation
Erythropoiesis
Lifecycle of Erythrocytes
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups.
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Factors Affecting Erythropoiesis
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow

