Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Rett's syndrome: pathophysiology and anesthesiological implications].

F M Häuser1, P Lukasewitz, A Wichert

  • 1Abteilung für Anästhesie und Intensivtherapie, Klinikum der Philipps-Universität Marburg.

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
|October 30, 1999
PubMed
Summary

Rett syndrome, a rare neurodevelopmental disorder affecting girls, causes loss of skills and severe impairments. This paper details its pathophysiology and anesthetic considerations for affected individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Telemetric monitoring of tracheal pressure after tracheal occlusion for treatment of severe congenital diaphragmatic hernia.

Archives of gynecology and obstetrics·2006
Same author

Computer simulation for ergonomic improvements in laparoscopic surgery.

Applied ergonomics·2005
Same author

An evaluation of a surgical telepresence system for an intrahospital local area network.

Journal of telemedicine and telecare·2005
Same author

Expanding the role of mammographers: a training strategy to enhance mammographer-patient interaction.

Breast disease·2005
Same author

Evaluation of the development of lung hypoplasia in the premature lamb.

Archives of gynecology and obstetrics·2004
Same author

Perioperative triggers for red cell transfusions.

Vox sanguinis·2002

Area of Science:

  • Neuroscience
  • Genetics
  • Pediatrics

Background:

  • Rett syndrome is a rare X-linked neurodevelopmental disorder primarily affecting females.
  • It is characterized by initial normal development followed by regression of acquired skills.

Observation:

  • The syndrome progresses through distinct stages, culminating in severe intellectual disability, motor deficits, and autonomic dysfunction.
  • Clinical manifestations include microcephaly, spasticity, epilepsy, and respiratory irregularities.

Findings:

  • The paper reviews the pathophysiology of Rett syndrome, linking it to genetic mutations on the X-chromosome.
  • A case report highlights specific anesthesiological challenges in patients with immature cardiorespiratory systems.

Implications:

Related Experiment Videos

  • Understanding Rett syndrome's pathophysiology is crucial for diagnosis and management.
  • Anesthetic management requires careful consideration of cardiorespiratory immaturity and potential complications like valproic acid-induced coagulopathy.