Related Experiment Video
Updated: Oct 18, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Excavatolides U-Z, new briarane diterpenes from the gorgonian briareum excavatum
1Department of Marine Resources and Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, Republic of China.
Abstract:
A recent study of the EtOAc extract of the gorgonian Briareum excavatum afforded six new diterpenes of the briarane skeleton, excavatolides U-Z (1-6). The structures and relative stereochemistry of metabolites 1-6 were assigned on the basis of NMR studies and chemical methods. The structure, including the relative configuration of excavatolide U (1), was further confirmed by a single-crystal X-ray analysis. Some of the excavatolides have displayed significant cytotoxicity toward P-388 and HT-29 tumor cells.
More Related Videos
Related Concept Videos
Drugs that Stabilize Microtubules
Diversity of Protists III
Drugs that Destabilize Microtubules
Anthelminthic Agents
Bioremediation
Inhibitors of Bacterial DNA Synthesis

