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Related Experiment Videos

Colitis after clindamycin therapy.

M Bain, H C Windell, A J Drinnan

    Journal of Oral Surgery (American Dental Association : 1965)
    |April 1, 1975
    PubMed
    Summary

    Clindamycin, prescribed for pericoronitis, caused severe colitis in a young patient. This case highlights the serious risks of clindamycin and lincomycin, urging dental professionals to use caution.

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    Area of Science:

    • Gastroenterology
    • Pharmacology
    • Dentistry

    Background:

    • Antibiotic-associated colitis is a serious potential complication.
    • Clindamycin and lincomycin are commonly used antibiotics in dentistry.
    • Pericoronitis is a common dental infection requiring antibiotic management.

    Purpose of the Study:

    • To report a case of severe colitis secondary to clindamycin use for pericoronitis.
    • To review the literature on colitis associated with lincomycin and clindamycin therapy.
    • To raise awareness among dental professionals about this adverse drug reaction.

    Main Methods:

    • Case report presentation.
    • Literature review of antibiotic-associated colitis.
    • Analysis of clindamycin and lincomycin adverse effects.

    Main Results:

    • A young patient developed severe colitis while on clindamycin for pericoronitis.
    • Literature confirms clindamycin and lincomycin as potential causes of serious colitis.
    • Vigorous treatment was required for the patient's colitis.

    Conclusions:

    • Clindamycin and lincomycin therapy can lead to severe, potentially life-threatening colitis.
    • Dental professionals must be aware of this risk and exercise caution when prescribing these antibiotics.
    • Careful patient selection and monitoring are crucial to prevent adverse outcomes.

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