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Chronic cholestasis associated with Turner's syndrome
A Floreani1, M Molaro, A Baragiotta
1Department of Surgical and Gastroenterological Sciences, University of Padova, Italy. aflor@uxi.unipd.it
Digestion
|November 5, 1999
Summary
Liver disease is rare in Turner's syndrome but can manifest as cholestasis. This study highlights varied liver expressions in Turner's syndrome patients, including primary sclerosing cholangitis and tumors.
Area of Science:
- Hepatology
- Endocrinology
- Genetics
Background:
- Turner's syndrome is a genetic condition typically affecting females.
- Liver abnormalities are infrequently reported in Turner's syndrome.
Observation:
- This study details three cases of Turner's syndrome presenting with cholestasis.
- One patient developed primary sclerosing cholangitis and two tumors.
Findings:
- Liver disease in Turner's syndrome can present with diverse manifestations.
- Cholestasis is a potential, though rare, hepatic complication.
Implications:
- Increased awareness of potential liver involvement in Turner's syndrome is warranted.
- Further research into the mechanisms of liver disease in Turner's syndrome is needed.