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Cell adhesion of Plesiomonas shigelloides
1Institut für Hygiene und Umweltmedizin, Klinikum der Johann-Wolfgang-von-Goethe-Universität Frankfurt, Germany.
Zentralblatt Fur Hygiene Und Umweltmedizin = International Journal of Hygiene and Environmental Medicine
|November 5, 1999
Summary
Plesiomonas shigelloides exhibits variable cell adhesion. Clinical isolates show higher adhesion than environmental strains, though less than Aeromonas, indicating potential virulence differences.
Area of Science:
- Microbiology
- Cell Biology
- Infectious Diseases
Background:
- Plesiomonas shigelloides is an opportunistic pathogen.
- Cell adhesion is a key factor in bacterial pathogenesis.
- Variability in P. shigelloides virulence factors is not well understood.
Purpose of the Study:
- To investigate the cell adhesion properties of Plesiomonas shigelloides.
- To compare the adhesion of clinical and environmental P. shigelloides isolates.
- To assess P. shigelloides adhesion in relation to other bacterial species.
Main Methods:
- INT-407 cell adhesion assay.
- Isolation of P. shigelloides from clinical and environmental sources (pond water, mud, water insects).
- Comparative analysis of adhesion levels.
Main Results:
- P. shigelloides demonstrated inconsistent cell adhesion in the INT-407 assay.
- Clinical P. shigelloides isolates showed regular and pronounced adhesion.
- Adhesion of clinical P. shigelloides was lower than clinical Aeromonas isolates.
- Environmental P. shigelloides isolates exhibited minimal to no cell adhesion.
Conclusions:
- P. shigelloides exhibits strain-dependent variations in cell adhesion.
- Clinical isolates possess enhanced adhesion capabilities compared to environmental strains.
- Adhesion differences may contribute to the variable pathogenicity of P. shigelloides.