Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flow limitation: an overview.

C Tantucci1, V Grassi

  • 1Clinica di Semeiotica Medica, University of Ancona, Italy.

Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
|November 5, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phenotyping OSAH patients during wakefulness.

Sleep & breathing = Schlaf & Atmung·2022
Same author

Computational simulation of TEVAR in the ascending aorta for optimal endograft selection: A patient-specific case study.

Computers in biology and medicine·2018
Same author

Performance of pile-up mitigation techniques for jets in [Formula: see text] collisions at [Formula: see text] TeV using the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

Measurement of the centrality dependence of the charged-particle pseudorapidity distribution in proton-lead collisions at [Formula: see text] TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

A systematic analysis of controlled clinical trials using the NiTi CAR™ compression ring in colorectal anastomoses.

Techniques in coloproctology·2017
Same author

A rare case of perforation of the subhepatic appendix by a toothpick in a patient with intestinal malrotation: laparoscopic approach.

Il Giornale di chirurgia·2016
Same journal

Spirometry after treatment completion for pulmonary tuberculosis - a necessity?

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Heart failure at the crossroads of climate change and environmental health: emerging risks, mechanistic insights, and future directions.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Aspiration pneumonia in stroke survivors: prevalence and clinical associations at Bolan Medical Complex.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

The silent fractures: unmasking osteoporosis in south Indian chronic obstructive pulmonary disease patients.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Vitamin D deficiency in patients with tuberculosis: prevalence, risk factors and treatment outcomes.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

A correlational study to assess the levels of adherence to treatment, illness perception and acceptance of illness in patients with coronary artery disease attending the outpatient departments at a tertiary care hospital.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
See all related articles

Expiratory flow limitation (EFL) is a condition where airflow peaks and cannot increase further. In certain conditions, EFL worsens breathing, leading to dynamic pulmonary hyperinflation and shortness of breath.

Area of Science:

  • Pulmonary Physiology
  • Respiratory Mechanics

Background:

  • Expiratory flow limitation (EFL) is a state where airflow cannot increase further, even with increased effort.
  • Factors like airway obstruction, expiratory flow rate, and body posture contribute to EFL.
  • Abnormal EFL during tidal breathing, especially at rest or during exercise, indicates significant respiratory impairment.

Purpose of the Study:

  • To explain the mechanisms by which EFL impacts respiratory mechanics.
  • To elucidate the relationship between EFL, dynamic pulmonary hyperinflation (DH), and dyspnea.
  • To discuss the therapeutic implications of managing EFL in chronic obstructive pulmonary disease (COPD).

Main Methods:

  • The study is a review of existing literature and physiological principles.
  • It analyzes the functional consequences of EFL on lung volumes and respiratory pressures.

Related Experiment Videos

  • It discusses the effects of interventions on EFL and associated symptoms.

    • Main Results:

    • EFL promotes dynamic pulmonary hyperinflation (DH) by increasing expiratory time and end-expiratory lung volume.
    • Breathing at higher lung volumes due to EFL increases the load on inspiratory muscles, causing weakness and dyspnea.
    • Treatments like bronchodilators and lung volume reduction surgery may not reverse EFL but can reduce DH and dyspnea by allowing EFL at lower lung volumes.

    Conclusions:

    • EFL significantly impairs respiratory function, leading to DH and exertional dyspnea.
    • Understanding EFL mechanisms is crucial for managing respiratory diseases like COPD.
    • Therapeutic strategies aim to mitigate the negative effects of EFL on breathing mechanics and symptoms.