Related Experiment Video

Updated: Aug 12, 2026

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy
13:01

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy

Published on: September 28, 2019

Pyloric ratio: efficacy in the diagnosis of hypertrophic pyloric stenosis

L H Lowe1, W J Banks, Y Shyr

  • 1Department of Radiology and Radiologic Sciences, Vanderbilt Children's Hospital, Nashville, Tennessee, USA.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|November 5, 1999
PubMed

Insights

A new pyloric ratio measurement accurately diagnoses hypertrophic pyloric stenosis in infants. This weight-independent indicator offers high sensitivity and specificity for diagnosing this common condition.

Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Imaging
  • Infant Health

Background:

  • Hypertrophic pyloric stenosis (HPS) is a common cause of infant vomiting.
  • Accurate diagnosis is crucial for timely intervention.
  • Current diagnostic methods may have limitations.

Purpose of the Study:

  • To define a weight-independent, sensitive, and specific measurement for diagnosing HPS.
  • To evaluate the pyloric ratio as a diagnostic tool.

Main Methods:

  • Retrospective review of 87 pediatric patients.
  • Calculation of the pyloric ratio (wall thickness/pyloric diameter).
  • Comparison of the pyloric ratio to patient weight and standard diagnostic criteria.

Main Results:

  • Average pyloric ratios were 0.205 in normal infants and 0.325 in HPS patients (P < 0.001).
  • A pyloric ratio cutoff of 0.27 achieved 96% sensitivity and 94% specificity.
  • The pyloric ratio demonstrated a linear relationship with weight in both normal and HPS groups.

Conclusions:

  • The pyloric ratio is a highly sensitive, specific, and weight-independent indicator for diagnosing HPS.
  • This measurement can aid in the accurate and efficient diagnosis of hypertrophic pyloric stenosis.

More Related Videos

Gastric Point of Care Ultrasound in Adults: Image Acquisition and Interpretation05:50

Gastric Point of Care Ultrasound in Adults: Image Acquisition and Interpretation

Published on: September 22, 2023

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia03:05

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia

Published on: February 16, 2024

Related Concept Videos

Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors01:24

Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors

Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI)  tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining. Bicarbonate,...
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...