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Related Experiment Videos

Personality change in dementia.

L Aitken1, S Simpson, A Burns

  • 1Stepping Hill Hospital, Stockport, England.

International Psychogeriatrics
|November 5, 1999
PubMed
Summary
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Personality changes are nearly universal in dementia patients, often negative, and linked to cognitive decline and neurological signs. This highlights the biological basis of personality shifts in Alzheimer

Area of Science:

  • Neuroscience
  • Psychiatry
  • Gerontology

Background:

  • Personality changes are common in dementia but require further investigation.
  • Understanding these changes is crucial for patient care and support.

Purpose of the Study:

  • To examine the prevalence and nature of personality change in dementia patients.
  • To explore the relationship between personality alterations and clinical factors.

Main Methods:

  • Assessed personality changes in 99 patients with Alzheimer type and multi-infarct dementia.
  • Utilized informant-rated inventories to compare pre- and post-dementia personality traits.

Main Results:

  • Personality change was almost universal and predominantly negative.

Related Experiment Videos

  • Changes correlated significantly with cognitive impairment severity, illness duration, and neurological signs.
  • Conclusions:

    • Personality alterations in dementia are widespread and biologically based.
    • Severity of cognitive impairment and neurological signs are key predictors of personality change.