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Related Experiment Videos

A fast 3D approach for coronary MRA.

R M Botnar1, M Stuber, P G Danias

  • 1Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA. rbotnar@caregroup.harvard.edu

Journal of Magnetic Resonance Imaging : JMRI
|November 5, 1999
PubMed
Summary

This study introduces an ultra-fast, free-breathing, three-dimensional (3D) coronary magnetic resonance angiography (MRA) technique. This advanced 3D coronary MRA achieves scan times under five minutes, offering improved imaging quality for coronary arteries.

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Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging
  • Medical Technology

Background:

  • Two-dimensional (2D) breath-hold coronary magnetic resonance angiography (MRA) is effective for proximal coronary arteries.
  • Free-breathing, navigator-gated/corrected 3D coronary MRA offers potential for higher signal-to-noise ratio (SNR) and improved slice acquisition.
  • Increased scan time remains a significant limitation for 3D coronary MRA techniques.

Purpose of the Study:

  • To implement and evaluate an ultra-fast, free-breathing, navigator-gated and corrected 3D coronary MRA technique.
  • To achieve scan times under 5 minutes for 3D coronary MRA.
  • To assess the feasibility and image quality of the developed technique in healthy subjects.

Main Methods:

  • Utilized a navigator-gated and corrected ECG-triggered ultra-fast 3D interleaved gradient echo planar imaging (TFE-EPI) sequence.

Related Experiment Videos

  • Acquired a 3D slab (20 slices, 1.5 mm reconstructed thickness) during free-breathing.
  • Employed specific parameters: TR 19 ms, effective TE 5.4 ms, acquisition window 38 ms, in-plane resolution 1.0-1.3 mm*1.5-1.9 mm.

    • Main Results:

    • Achieved an average scan time of 2:57 +/- 0:51 minutes for the entire 3D dataset.
    • Successfully visualized the entire left main (LM) and significant portions of the left anterior descending (LAD) and right coronary artery (RCA).
    • Demonstrated excellent myocardial suppression with favorable contrast-to-noise ratios (5.0 +/- 2.3 for LM/LAD, 8.0 +/- 2.9 for RCA).

    Conclusions:

    • Presented a novel free-breathing 3D coronary MRA approach with scan times superior to 2D methods.
    • Leveraged 3D acquisition benefits (enhanced SNR) and thin-slice advantages for robust image quality.
    • The technique's speed and quality suggest potential utility for coronary artery screening and anomaly detection.