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Updated: Feb 25, 2026
3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
Published on: August 4, 2020
[Rehabilitation, using prosthetic implants, in patients with cancer of the oral cavity]
D Coppola1, F Andaloro, L Levrini
1Facoltà di Medicina e Chirurgia, Cattedra di Clinica Odontostomatologica, Università degli Studi dell'Insubria.
Background:
The number of patients treated for neoplasms of the oral cavity (by surgery and/or radiotherapy) requiring prosthesis rehabilitation using osteointegrated implants is increasing greatly. The objective of this research is to examine the correlation between prosthesis rehabilitation using osteointegrated implants, radiotherapy and the use of hyperbaric oxygen treatment in order to reduce the risk of osteoradionecrosis.
Methods:
Research was carried out on 13 patients with 58 implants. The patients were divided into three sample groups: group A patients underwent radiotherapy (10 implants), group B patients did not undergo radiotherapy (29 implants) and group C patients first underwent radiotherapy and then hyperbaric oxygen treatment (19 implants). The group C patients first underwent hyperbaric oxygen treatment at 2.5 atmospheres. The osteointegrated implants were then applied and hyperbaric oxygen treatment was carried out again over 20-30 postoperative sittings without any other treatment between the sittings. The whole test period lasted 24 months.
Results:
Only two implants were lost out of the 58 implants and they were in the group that had undergone radiotherapy.
Conclusions:
The results show how pre and postoperative hyperbaric oxygen treatment improves the success rate of osteointegrated implants in mandibular areas that had previously undergone radiotherapy. Moreover, the stability of the prostheses that are fixed to the implants is greatly improved compared to conventional methods.
