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Chromosome 16 inversion-associated translocation: two new cases.

O Maarek¹, A Salabelle, M B Le Coniat

¹Laboratoire Central d'Hématologie Hôpital Saint Louis, Paris, France.

Cancer Genetics and Cytogenetics

|November 5, 1999

Summary

Chromosome 16 rearrangements involving inversion and translocation were analyzed. Fluorescence in situ hybridization (FISH) proved crucial for identifying these complex genetic changes, highlighting potential diagnostic challenges.

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Area of Science:

Genetics
Cytogenetics
Molecular Biology

Background:

Chromosome 16 rearrangements, including inversions and translocations, can lead to complex genetic alterations.
Accurate identification of these rearrangements is essential for understanding their clinical implications.