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Population genetics of nine short tandem repeat (STR) loci - DNA typing using the AmpFlSTR profiler PCR amplification
M Hantschel1, R Hausmann, T Lederer
1Insitute of Legal Medicine, University of Erlangen-Nürnberg, Universitätsstrasse 22, D-91054 Erlangen, Germany.
International Journal of Legal Medicine
|November 7, 1999
Abstract:
Frequency data for nine short tandem repeat (STR) loci were collected from 130 unrelated Caucasians from North Bavaria using the AmpFlSTR Profiler multiplex system. The loci D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820 and the sex test amelogenin were investigated. Allele frequencies, rates of heterozygosity and the discrimination power of the combined systems were calculated by statistical analysis. Except for D5S818 all loci met Hardy-Weinberg expectations.