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Chronic lymphocytic leukemia
1Medicine Branch and Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland 20892, USA.
The Oncologist
|November 7, 1999
Abstract:
The diagnosis and management of chronic lymphocytic leukemia (CLL) is reviewed, including the basic aspects of epidemiology, molecular biology, and cytogenetics with clinical relevance. The importance of immunophenotype in the differential diagnosis of other lymphoproliferative disorders related to CLL, staging, prognostic factors, promising new drugs, and approaches is summarized.