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Intrathecal ropivacaine for ambulatory surgery.
P E Gautier1, M De Kock, A Van Steenberge
1Department of Anesthesiology, Clinique Ste. Anne-St. Remi, Brussels, Belgium.
Anesthesiology
|November 7, 1999
Summary
Intrathecal ropivacaine 12 mg offers sensory and motor block comparable to bupivacaine 8 mg for ambulatory surgery. However, this dose of ropivacaine provides no significant advantage over bupivacaine.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Evaluating intrathecal ropivacaine for ambulatory surgery.
- Assessing anesthetic agents for outpatient procedures.
Purpose of the Study:
- Compare intrathecal ropivacaine doses with bupivacaine for ambulatory knee arthroscopy.
- Determine optimal ropivacaine dosage for surgical anesthesia.
Main Methods:
- 150 patients (ASA physical status 1) received intrathecal isobaric solutions: bupivacaine 8 mg or ropivacaine 8, 10, 12, or 14 mg.
- Recorded sensory and motor block characteristics and duration.
- Monitored for transient neurologic symptoms.
Main Results:
- Ropivacaine 10 mg resulted in shorter sensory anesthesia and motor block than bupivacaine 8 mg, with lower intraoperative analgesia quality.
- Ropivacaine 12 mg provided sensory and motor block comparable to bupivacaine 8 mg.
- Higher doses of ropivacaine did not significantly improve block characteristics but increased time to void.
Conclusions:
- Intrathecal ropivacaine 12 mg is comparable to bupivacaine 8 mg for ambulatory surgery.
- At equivalent doses, ropivacaine does not offer a significant advantage over bupivacaine.
- No transient radicular irritation was observed with ropivacaine.