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The club-shaped cord terminus in siblings with caudal agenesis: MRI
O Unal1, M E Sakarya, H Arslan
1Department of Radiology, Yüzüncü Yil University Faculty of Medicine, Maraş Cad. Van, 65200, Turkey.
Neuroradiology
|November 7, 1999
Abstract:
We report a rare instance of caudal agenesis occurring in siblings, with MRI. Both our patients had a club-shaped spinal cord, ending at T11. Radiological and urological findings are presented.
Insights
This study details a rare case of caudal agenesis in siblings, a condition affecting spinal cord development. Both patients exhibited a club-shaped spinal cord ending at the T11 vertebra.
Area of Science:
- Medical imaging
- Genetics
- Developmental biology
Background:
- Caudal agenesis is a rare congenital disorder characterized by incomplete development of the lower spine and spinal cord.
- Genetic factors are implicated in some cases of caudal agenesis, but familial occurrences are exceptionally uncommon.
Observation:
- This report describes a rare instance of caudal agenesis observed in siblings.
- Magnetic resonance imaging (MRI) was utilized to evaluate the spinal cord morphology in both affected individuals.
Findings:
- Both siblings presented with a distinct club-shaped spinal cord.
- The spinal cord in both patients terminated prematurely at the T11 vertebral level.
- Associated radiological and urological findings were documented and are presented.
Implications:
- This familial case contributes to understanding the genetic and developmental underpinnings of caudal agenesis.
- Further research into familial patterns may elucidate specific genetic mutations or environmental factors.
- Detailed radiological and urological data can aid in clinical management and prognosis for affected families.