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Related Experiment Videos

Necrotizing otitis externa caused by Staphylococcus epidermidis.

D Soldati1, A Mudry, P Monnier

  • 1Department of Otolaryngology, Head and Neck Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Bugnon 46, CH-1011 Lausanne, Switzerland.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|November 7, 1999
PubMed
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Malignant necrotizing otitis externa (MNOE) caused by Staphylococcus epidermidis, a typically non-pathogenic bacterium, was successfully treated. Aggressive surgical and antibiotic interventions resolved the infection, though hearing loss occurred in one ear.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Microbiology

Background:

  • Malignant necrotizing otitis externa (MNOE) is a severe infection of the external auditory canal.
  • Staphylococcus epidermidis is typically a commensal organism, rarely causing invasive infections.

Observation:

  • A 58-year-old man with a history of bilateral exostoses surgery developed persistent otalgia, hearing loss, and ear discharge.
  • Cultures consistently isolated Staphylococcus epidermidis, initially overlooked due to co-infection with other microbes.
  • Previous antibiotic and antifungal treatments were ineffective.

Findings:

  • MNOE was diagnosed and attributed to Staphylococcus epidermidis.
  • A comprehensive treatment regimen including surgical debridement, mastoidectomy, and multiple antibiotics was implemented.

Related Experiment Videos

  • Successful resolution of otitis externa was achieved after aggressive treatment.

    • Implications:

    • This case highlights Staphylococcus epidermidis as a potential pathogen in MNOE.
    • Aggressive surgical and targeted antistaphylococcal therapy can be effective in refractory MNOE cases.
    • Ototoxicity is a potential complication of vancomycin treatment for MNOE.