Related Experiment Videos
[Cancer metastasis and extracellular matrix]
1Institute for Molecular Science of Medicine, Aichi Medical University, Japan.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 30, 1999
Abstract:
We investigated the roles of the extracellular matrix, especially of hyaluronan, in cancer metastasis. A positive relationship was shown between hyaluronan synthetic activity and the metastatic ability of cancer cells by manipulating regulation of gene expression of hyaluronan synthases. These techniques may provide future therapeutic methods for cancer metastasis.