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Factor XI deficiency: literature review and case presentation
1Brooklyn Veterans Affairs Medical Center, New York 11209, USA.
Summary
Factor XI deficiency is a rare bleeding disorder. Proper laboratory testing and management are crucial for patients undergoing surgery or experiencing trauma.
Area of Science:
- Hematology
- Coagulation Disorders
- Hereditary Diseases
Background:
- Factor XI deficiency is a rare inherited bleeding disorder impacting the intrinsic coagulation pathway.
- Understanding its pathophysiology is vital for managing patients and preventing complications.
Observation:
- This case presentation focuses on a patient with factor XI deficiency.
- It highlights the importance of accurate diagnosis and management strategies.
Findings:
- The study details laboratory criteria essential for identifying factor XI deficiency.
- It also discusses serum assaying techniques for effective patient management.
Implications:
- Appropriate management of factor XI deficiency can prevent hazardous sequelae in preoperative and post-traumatic patients.
- This knowledge aids clinicians in optimizing patient care for bleeding disorders.