Related Experiment Video
Updated: Jul 31, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
Published on: September 25, 2017
Formation of N-Nitrosoterbuthylazine and N-Nitrosoterbutryn in a Model System of Soil Water
Trevisan1, Graviani, Del Re AA
1Dipartimento di Scienze Molecolari Agroalimentari and Dipartimento di Farmacologia, Chemioterapia e Tossicologia Medica, Centro CNR Farmacologia Infrastrutture Cellulari, Università di Milano, I-20133 Milano, Italy, and Istituto di Chimica Agraria e Ambientale, Università Cattolica del Sacro Cuore, Piacenza, Italy.
Abstract:
The s-triazines terbutryn and terbuthylazine are currently used in Italy for weed control. A possible reaction of these compounds in the environment is N-nitrosation. Experiments performed in 10 mM CaCl(2) as a model of soil water indicated that N-nitrosation is favored only at low pH values and that the N-nitroso derivatives are fairly stable. In the presence of soil either parent compounds or N-nitroso derivatives are strongly adsorbed. These results seem to indicate that the possibility of formation of N-nitrosoterbuthylazine and N-nitrosoterbutryn in common agricultural soil is very remote.
More Related Videos
07:32Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System
Published on: January 30, 2019
08:05Measurement of the Potential Rates of Dissimilatory Nitrate Reduction to Ammonium Based on 14NH4+/15NH4+ Analyses via Sequential Conversion to N2O
Published on: October 7, 2020
Related Concept Videos
Rate-Determining Steps
In a multistep reaction mechanism, one of the elementary steps progresses significantly slower than the others. This slowest step is called the rate-limiting step (or rate-determining step). A reaction cannot proceed faster than its slowest step, and hence, the rate-determining step limits the overall reaction rate.
The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...
Overview of Nitrogen Metabolism
The largest pool of nitrogen available in the terrestrial ecosystem is gaseous nitrogen (N2) from the air, but this nitrogen...
Electrophilic Aromatic Substitution: Nitration of Benzene
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by water loss...
2° Amines to N-Nitrosamines: Reaction with NaNO2
Inorganic Nitrogen Assimilation