Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breast boost--why, how, when...?

J Hammer1, J J Mazeron, E Van Limbergen

  • 1Department of Radiation Oncology, Krankenhaus der Barmherzigen Schwestern, Linz, Austria. josef.hammer@bhs.at

Strahlentherapie Und Onkologie : Organ Der Deutschen Rontgengesellschaft ... [Et Al]
|November 11, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temporal order of activations and interactions during arithmetic calculations measured by intracranial electrophysiological recordings in the human brain.

Scientific reports·2026
Same author

Evaluation of brachytherapy applicators and their association with morbidity and local control in cervix cancer: An EMBRACE I analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2025
Same author

Hohlraum Reheating from Burning NIF Implosions.

Physical review letters·2024
Same author

[Myalgia and fever in a 35-year-old woman].

La Revue de medecine interne·2023
Same author

Vaginal changes, sexual functioning and distress of women with locally advanced cervical cancer treated in the EMBRACE vaginal morbidity substudy.

Gynecologic oncology·2023
Same author

Tunable and state-preserving frequency conversion of single photons in hydrogen.

Science (New York, N.Y.)·2022
Same journal

Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same journal

[Evolution of metastases in non-small-cell lung cancer: preliminary results from the TRACERx-PEACE study].

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same journal

[SAKK 09/10: dose-intensified salvage radiotherapy for biochemical recurrence after prostatectomy-no benefit, but additional toxicity?]

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same journal

Helical intensity-modulated radiation therapy vs. C-arm-based volumetric modulated arc therapy for sinonasal tumours: organ at risk sparing and treatment efficiency.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same journal

Delta radiomics for predicting early radiation-induced lung injury after thoracic radiotherapy: a retrospective paired-CT study.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same journal

Individualized radiotherapy of bone metastases from prostate cancer: time trends and 5-year survival results.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
See all related articles

The optimal use of radiation boost therapy in breast-conserving surgery remains unclear. Further research is needed to clarify boost indications and techniques for improved patient outcomes.

Area of Science:

  • Oncology
  • Radiation Oncology
  • Surgical Oncology

Background:

  • Breast conservation therapy (BCT) using tumorectomy or quadrantectomy with external beam radiotherapy is standard for small breast carcinomas.
  • The role and techniques for radiation boost therapy in BCT are not well-defined, leading to controversy.
  • High-dose-rate (HDR) interstitial brachytherapy is increasingly used for boost treatment, raising concerns about long-term morbidity.

Purpose of the Study:

  • To provide recommendations on the indication, timing, target volume, dose, and dose rate for radiation boost in BCT.
  • To address the controversy surrounding different boost techniques, specifically electron versus interstitial boost.
  • To discuss the implications of HDR interstitial brachytherapy for boost treatment in breast cancer.

Main Methods:

Related Experiment Videos

  • This article presents a perspective and recommendations based on current knowledge and ongoing research.
  • It reviews the existing controversies and considerations regarding radiation boost techniques.
  • It highlights the need for further clinical trials to refine treatment protocols.

Main Results:

  • The EORTC trial 22881/10882 is expected to provide more data on boost indications.
  • Careful patient selection and refinement of surgical and radiotherapy techniques can improve clinical and cosmetic results in BCT.
  • There is a need for prospective trials comparing different boost techniques and morphologic criteria.

Conclusions:

  • Further research is essential to establish clear guidelines for radiation boost indications and techniques in breast conservation therapy.
  • Optimizing boost strategies may enhance both the efficacy and aesthetic outcomes of BCT.
  • Comparative trials are crucial for guiding clinical decisions regarding boost therapy in breast cancer management.