Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Topical anesthesia for office hysteroscopy. A prospective, randomized study comparing two modalities.

F Zullo1, M Pellicano, C M Stigliano

  • 1Department of Obstetrics and Gynecology, University of Naples Federico II, Italy.

The Journal of Reproductive Medicine
|November 11, 1999
PubMed
Summary

Prilocaine plus lidocaine cream effectively reduced pain during diagnostic hysteroscopy compared to lidocaine spray and no anesthesia. This topical anesthesia also shortened procedure times and decreased post-procedure shoulder pain.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Towards a representative and affordable national survey on radon in dwellings: a new methodological approach with findings from Italy.

Environmental research·2026
Same author

Decoding indoor radon: An explainable AI approach to quantifying building, environmental, and inhabitants' contributions.

The Science of the total environment·2025
Same author

Adverse neonatal outcomes in small-for-gestational age twins identified using twin vs singleton growth charts: systematic review and meta-analysis.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Development of a methodology for dose assessment and estimate of amount of NORM residues disposable in a conventional landfill.

Journal of environmental radioactivity·2024
Same author

Models of radon exhalation from building structures: General and case-specific solutions.

The Science of the total environment·2023
Same author

Extreme reverse seasonal variations of indoor radon concentration and possible implications on some measurement protocols and remedial strategies.

Environmental pollution (Barking, Essex : 1987)·2023

Area of Science:

  • Gynecology
  • Pain Management
  • Anesthesiology

Background:

  • Diagnostic hysteroscopy is a common gynecological procedure.
  • Pain and discomfort can be significant during hysteroscopy, impacting patient experience.
  • Effective pain control is crucial for improving patient tolerance and procedural outcomes.

Purpose of the Study:

  • To compare the efficacy of prilocaine plus lidocaine cream versus lidocaine spray for local anesthesia during diagnostic hysteroscopy.
  • To evaluate the impact of these anesthetic modalities on pain control at different procedural stages and overall procedure duration.
  • To assess post-procedural shoulder pain and vasovagal reactions.

Main Methods:

  • A randomized controlled trial involving 180 women undergoing diagnostic hysteroscopy.

Related Experiment Videos

  • Participants were allocated to receive prilocaine plus lidocaine cream (Group A), lidocaine spray (Group B), or no anesthesia (Group C).
  • Pain intensity, procedure duration, and shoulder pain were recorded using a four-point pain scale.
  • Main Results:

    • Prilocaine plus lidocaine cream significantly reduced procedure duration compared to lidocaine spray and no anesthesia.
    • Group A showed a significant reduction in pain during tenaculum placement compared to Groups B and C.
    • Both anesthetic groups reported significantly lower rates of severe pain and vasovagal reactions than the control group, with Group A also experiencing less post-procedure shoulder pain.

    Conclusions:

    • Local anesthesia provides significant benefits for diagnostic hysteroscopy, particularly for more challenging procedures.
    • Prilocaine plus lidocaine cream demonstrates superior efficacy over lidocaine spray in mitigating pain during tenaculum placement and reducing post-procedure shoulder pain.
    • Topical anesthesia with prilocaine plus lidocaine cream is a valuable option for enhancing patient comfort during diagnostic hysteroscopy.