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Comorbidity in arthritis.

S E Gabriel1, C S Crowson, W M O'Fallon

  • 1Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA. gabriel.sherine@mayo.edu

The Journal of Rheumatology
|November 11, 1999
PubMed
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Patients with rheumatoid arthritis (RA) and osteoarthritis (OA) experience a higher burden of illness than controls. This burden increases over time, especially for RA patients, highlighting the need for specialized chronic disease care.

Area of Science:

  • Epidemiology of rheumatic diseases.
  • Chronic disease burden assessment.
  • Population health studies.

Background:

  • Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic conditions.
  • Understanding comorbidities in arthritis patients is crucial for effective healthcare.
  • Comparative studies with community controls are needed to assess disease burden.

Purpose of the Study:

  • To compare the frequency of selected comorbidities in RA and OA patients versus controls.
  • To identify specific comorbidities associated with RA and OA.
  • To evaluate the longitudinal change in comorbidity burden in arthritis patients.

Main Methods:

  • Utilized population-based cohorts from the Rochester Epidemiology Project.
  • Included RA, OA, and age/sex-matched community controls from 1965, 1975, and 1985.

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  • Longitudinal follow-up with medical record review, assessing comorbidity using Charlson and ICED indices.

    • Main Results:

    • RA patients showed increased risk for congestive heart failure, chronic pulmonary disease, dementia, and peptic ulcer disease.
    • OA patients had a higher risk of peptic ulcer disease and renal disease.
    • Age, male sex, baseline comorbidity, and RA significantly predicted increased comorbidity over time.

    Conclusions:

    • Arthritis patients, particularly those with RA, face a greater and increasing burden of illness compared to non-arthritic individuals.
    • The findings underscore the growing importance of specialized chronic disease management for RA patients.
    • Future healthcare strategies must address the escalating comorbidity burden in rheumatic diseases.