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Regulation of actin dynamics: The LIM kinase connection
1Centre for Molecular Medicine, Royal Free and University College Medical School, Rayne Institute, 5 University Street, London, WC1E 6JJ, UK.
Current Biology : CB
|November 11, 1999
Abstract:
A signalling pathway has recently been delineated that connects Rho-family GTPases to the cytoskeleton via LIM kinase and the F-actin depolymerising protein cofilin. The existence of this pathway helps to explain some of the effects of LIM kinase and cofilin in the control of actin dynamics.