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The serotonin precursor 5-hydroxytryptophan elevates serum leptin levels in mice

J Yamada1, Y Sugimoto, M Ujikawa

  • 1Department of Pharmacology, Kobe Pharmaceutical University, Motoyamakita-machi, Higashinada-ku, Kobe, Japan. j-yamada@kobepharma-u.ac.jp

European Journal of Pharmacology
|November 11, 1999
PubMed

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Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...