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Gemcitabine and cancer of the pancreas: new preparation. Helpful or not?
Prescrire International
|November 11, 1999
Abstract:
(1) The clinical file of gemcitabine in locally advanced metastatic adenocarcinoma of the pancreas mainly comprises one comparative trial versus 5 fluorouracil that shows the superiority of gemcitabine on a mixed end point (pain, functional capacities, weight). (2) In this trial haematotoxicity (anaemia and neutropenia) and nausea and vomiting were more common on gemcitabine.
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Assessment:
Assessment: