Phosphatidylinositol-3-OH kinases are Rab5 effectors

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.

Oncogene·2011

Regulation of class III (Vps34) PI3Ks.

Biochemical Society transactions·2007

Regulation of class IA PI3Ks.

Biochemical Society transactions·2007

Human VPS34 is required for internal vesicle formation within multivesicular endosomes.

The Journal of cell biology·2002

Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER.

FEBS letters·2001

Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteins.

Bioconjugate chemistry·2001

An EZH2-SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis.

Nature cell biology·2026

Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia.

Nature cell biology·2026

Advanced imaging of membrane contact sites.

Nature cell biology·2026

Mega-enhancers compartmentalize transcriptionally active long genes in the brain.

Nature cell biology·2026

The mitochondria enzyme OGDH defends against disulfidptosis by licensing METTL3-regulated NRF2 translation.

Nature cell biology·2026

Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis.

Nature cell biology·2026

Insights into the activity, production, and signaling circuits of homoserine lactones in mammalian cells.

iScience·2026

A conserved residue in the histidine kinase BceS tunes bacitracin stress responses in Bacillus subtilis.

Access microbiology·2026

Functional Specialization of Clathrin-Independent Endocytic Routes: Mechanisms and Cellular Roles.

Traffic (Copenhagen, Denmark)·2026

The calcium-binding protein CSE links Ca2+ signaling with cell-cell communication in cyanobacteria.

The EMBO journal·2026

Mathematical and Computational Models of Biochemical Reactions and Cell Signaling-From Ordinary Differential Equations to Machine Learning.

International journal of molecular sciences·2026

Regulation of Translation by PKA Signaling Pathway.

International journal of molecular sciences·2026

Related Experiment Videos

Phosphatidylinositol-3-OH kinases are Rab5 effectors

Related Concept Videos

Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.

Regulation of class III (Vps34) PI3Ks.

Regulation of class IA PI3Ks.

Human VPS34 is required for internal vesicle formation within multivesicular endosomes.

Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER.

Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteins.

An EZH2-SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis.

Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia.

Advanced imaging of membrane contact sites.

Mega-enhancers compartmentalize transcriptionally active long genes in the brain.

The mitochondria enzyme OGDH defends against disulfidptosis by licensing METTL3-regulated NRF2 translation.

Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis.

Insights into the activity, production, and signaling circuits of homoserine lactones in mammalian cells.

A conserved residue in the histidine kinase BceS tunes bacitracin stress responses in Bacillus subtilis.

Functional Specialization of Clathrin-Independent Endocytic Routes: Mechanisms and Cellular Roles.

The calcium-binding protein CSE links Ca2+ signaling with cell-cell communication in cyanobacteria.

Mathematical and Computational Models of Biochemical Reactions and Cell Signaling-From Ordinary Differential Equations to Machine Learning.

Regulation of Translation by PKA Signaling Pathway.

Related Experiment Videos

Phosphatidylinositol-3-OH kinases are Rab5 effectors

Related Concept Videos

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