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[Treatment of solid tumor by a direct electric current]
1Dept. of Surgery II, Nagoya University School of Medicine.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 24, 1999
Summary
Direct electric current therapy achieved a 4-year remission in a laryngeal sarcoma patient who refused surgery. This innovative treatment for solid tumors shows promise, with ongoing research into its mechanisms.
Area of Science:
- Oncology
- Medical Physics
- Electrophysiology
Background:
- Laryngeal sarcoma is a rare malignancy requiring effective treatment strategies.
- Conventional treatments like surgery and radiotherapy have limitations and side effects.
- This case report explores an alternative therapeutic approach for laryngeal sarcoma.
Observation:
- A 37-year-old female diagnosed with laryngeal sarcoma refused total laryngectomy.
- Initial Cobalt treatment yielded no significant improvement.
- Direct electric current therapy was administered percutaneously under CT guidance, followed by a bronchoscopic-guided session.
Findings:
- The patient achieved a remission lasting over 4 years with no recurrence.
- Direct electric current therapy led to tumor regression and symptom resolution (hoarseness).
- Previous studies show a 25% complete response and 50% partial response rate in over 8,000 solid tumor cases treated with direct electric current.
Implications:
- Direct electric current therapy presents a potential minimally invasive treatment option for solid tumors.
- Further research into the mechanism of action, including observed apoptosis in animal studies, is warranted.
- This therapy could become a recognized method for treating various solid malignancies.