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[Intratumoral ethanol injection therapy using endoscopic video information system]
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 24, 1999
Summary
Bronchoscopic ethanol injection (BEI) therapy effectively dilates airways and achieves hemostasis for endobronchial tumors. Using an endoscopic video information system (EVIS) minimizes adverse effects like coughing from ethanol leaks.
Area of Science:
- Pulmonology
- Interventional Bronchoscopy
- Oncology
Context:
- Endobronchial malignant tumors can cause airway obstruction and bleeding.
- Bronchoscopic ethanol injection (BEI) is a cost-effective treatment option.
- Ethanol leaks pose risks of coughing and bronchial wall erosion.
Purpose:
- To evaluate the efficacy and safety of BEI therapy for endobronchial malignant tumors.
- To assess the role of an endoscopic video information system (EVIS) in managing BEI.
- To determine optimal patient selection for BEI therapy.
Summary:
- Eight patients with endobronchial malignant tumors underwent BEI therapy using EVIS.
- Ethanol (99%) was injected into tumors, followed by necrotic tissue removal.
- Tumor degeneration and removal were repeated until airway obstruction or bleeding was controlled.
Impact:
- BEI therapy, guided by EVIS, relieved airway obstruction and atelectasis in 4 cases.
- Hemostasis was achieved in 2 cases; effectiveness was higher for polypoid/nodular tumors.
- Minor adverse effects (coughing) were manageable, indicating BEI's utility and cost-effectiveness.