Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Studies on small intestinal obstruction.

U Ohman

    Acta Chirurgica Scandinavica. Supplementum
    |January 1, 1975
    PubMed
    Summary

    Small bowel obstruction in cats causes moderate intestinal distension but preserves bowel activity and microcirculation. Decompression rapidly improves viability, with microcirculatory function only failing at extreme pressures.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Actinomyces naeslundii displays variant fimP and fimA fimbrial subunit genes corresponding to different types of acidic proline-rich protein and beta-linked galactosamine binding specificity.

    Infection and immunity·1998
    Same author

    Drug and alcohol use among injured motor vehicle drivers in Sweden: prevalence, driver, crash, and injury characteristics.

    Alcoholism, clinical and experimental research·1997
    Same author

    [Where should surgery for rectal cancer be performed?].

    Lakartidningen·1994
    Same author

    [Defibrillation of heart fibrillation. Life-saving equipment in ambulances used in sparsely populated areas].

    Lakartidningen·1994
    Same author

    Oral treatment with RU 41.740 (Biostim) in patients with advanced colorectal cancer: influence on the blood lymphocyte population.

    International journal of immunopharmacology·1989
    Same author

    [Sphincter-preserving surgery in rectal cancer].

    Lakartidningen·1987

    Area of Science:

    • Veterinary Medicine
    • Gastroenterology
    • Surgical Physiology

    Background:

    • Intestinal obstruction is a common surgical emergency in cats.
    • Understanding the physiological impact of obstruction and decompression is crucial for treatment.
    • Previous studies have not fully elucidated the microcirculatory and hemodynamic responses in feline intestinal obstruction.

    Purpose of the Study:

    • To investigate the effects of simple small-bowel obstruction and subsequent decompression on feline intestinal hemodynamics and microcirculation.
    • To determine the intraluminal pressure thresholds that compromise intestinal viability.
    • To assess the impact of varying distension levels on vascular resistance and capillary filtration.

    Main Methods:

    • In vivo and in vitro studies were conducted on cats with experimentally induced small-bowel obstruction.
    • Hemodynamic and microcirculatory parameters were evaluated before, during, and after obstruction and decompression.
    • Intraluminal pressures were manipulated to simulate varying degrees of distension.

    Main Results:

    • Simple obstruction caused modest intestinal distension with mild increases in intraluminal pressure (5-10 mmHg).
    • Bowel activity persisted for up to 72 hours and responded to stimulation.
    • Decompression rapidly restored intestinal viability, with no significant differences in microcirculation between obstructed and non-obstructed states post-release.
    • Severe distension (100 mmHg) drastically reduced blood flow and capillary surface area, but microcirculation was maintained until unphysiologic pressures were applied.
    • Moderate distension increased vascular resistance but did not compromise oxygen consumption or capillary filtration in the long term.

    Conclusions:

    • Feline small-bowel obstruction primarily involves distension rather than high pressure.
    • Intestinal viability is rapidly restored upon decompression.
    • The intestinal microcirculation remains functional until extremely high intraluminal pressures are reached.
    • Moderate, sustained distension does not threaten overall bowel viability.

    Related Experiment Videos