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Genetically manipulated animals and their use in experimental research
R Ge1
1Department of Biological Sciences, Faculty of Science, National University of Singapore. dbsgerw@nus.edu.sg
Annals of the Academy of Medicine, Singapore
|November 24, 1999
Summary
Genetically engineered animal models, including transgenic and knockout organisms, are vital for understanding gene function and developing new therapies for human diseases.
Area of Science:
- Molecular Biology
- Genetics
- Biotechnology
Background:
- Genetically manipulated animals are crucial for biological and medical research.
- Transgenic and gene-targeting (knockout) technologies have advanced our understanding of gene function.
Purpose of the Study:
- To provide an overview of the development of genetically manipulated animals.
- To highlight their applications in biological and medical research.
Main Methods:
- Review of transgenic technology.
- Review of gene-targeting (knockout) technology.
Main Results:
- Genetically manipulated animals significantly enhance the understanding of gene function and regulation.
- These models are increasingly used in human disease studies and drug development.
Conclusions:
- Genetically manipulated animals are indispensable tools in modern biological and medical research.
- Their continued development promises further breakthroughs in understanding and treating diseases.