Immunohistochemistry applied to the study of bone marrow Gaucher's cells: a case report
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Automated Quantification of Hematopoietic Cell – Stromal Cell Interactions in Histological Images of Undecalcified Bone
Published on: April 8, 2015
R Alterini1, L Rigacci, S Stefanacci
1Department of Haematology, University of Florence, Italy.
European Journal of Histochemistry : EJH
|November 24, 1999
Abstract:
Gaucher's disease is frequently associated with immunologic abnormalities, e.g. hypergammaglobulinemia, polyclonal gammopathy and benign monoclonal gammopathy. A patient with Gaucher's disease and a selective accumulation of IgM k in Gaucher's cells without serum monoclonal gammopathies is described. The selective accumulation is detected by immunohistochemistry analysis performed on cryostat bone marrow biopsies.
