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Regulation of gene expression by fatty acids
1Endocrinologie Métabolisme et Développement, CNRS UPR 1524, Meudon-Bellevue, France. pegorier@infobiogen.fr
Current Opinion in Clinical Nutrition and Metabolic Care
|November 24, 1999
Abstract:
Long-chain fatty acids regulate the transcription of several genes encoding proteins involved in energetic metabolism. This review discusses the relative contribution of free fatty acids or their coenzyme A ester as metabolite signals and the possibility that the control of gene transcription could be independent of the activation of peroxisome proliferator-activated receptors.