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Related Experiment Videos

Trace element deficiency and toxicity.

A Van Gossum1, J Neve

  • 1Department of Hepato-Gastroenterology and Pancreatology, Erasme Hospital, Brussels, Belgium. andre.van.gossum@skynet.be

Current Opinion in Clinical Nutrition and Metabolic Care
|November 24, 1999
PubMed
Summary

Trace element deficiencies, like iron and iodine, pose significant health risks globally, particularly in developing nations. This review highlights recent findings on trace element imbalances and their health implications.

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Area of Science:

  • Biochemistry
  • Human Physiology
  • Nutritional Science

Background:

  • Trace elements are crucial for enzymatic activities, immune function, and physiological processes.
  • Deficiencies in essential trace elements like iron and iodine remain significant global health issues, especially in developing countries.
  • Certain populations are at higher risk for developing trace element deficiencies.

Purpose of the Study:

  • To review recent data on the roles of trace elements in health and disease.
  • To discuss the implications of trace element deficiency and toxicity in various clinical contexts.
  • To highlight emerging findings from supplementation studies confirming the role of trace element deficiency.

Main Methods:

  • Literature review of recent scientific data on trace elements.

Related Experiment Videos

  • Analysis of studies investigating trace element deficiency and toxicity.
  • Synthesis of information regarding clinical manifestations and supplementation outcomes.
  • Main Results:

    • Trace element deficiency is implicated in various clinical conditions, with supplementation studies providing confirmation.
    • While rare, trace element toxicity, such as manganese toxicity in parenteral nutrition patients, can occur.
    • The review synthesizes current knowledge on both deficiency and toxicity of trace elements.

    Conclusions:

    • Trace elements play vital roles in human health, and their imbalances can lead to significant health problems.
    • Understanding trace element status is critical for public health, particularly in vulnerable populations.
    • Further research and clinical attention are warranted for both trace element deficiency and toxicity.