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Nutrients, age and cognitive function.

W J Riedel1, B L Jorissen

  • 1Experimental Psychopharmacology Unit, Maastricht University, The Netherlands. wim.riedel@np.unimaas.nl

Current Opinion in Clinical Nutrition and Metabolic Care
|November 24, 1999
PubMed
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Nutritional supplements like beta-carotene and alpha-tocopherol may benefit cognitive function in older adults. Proper diet and certain supplements show modest but positive effects on cognition.

Area of Science:

  • Gerontology
  • Nutritional Neuroscience
  • Cognitive Science

Background:

  • Nutritional status is linked to cognitive functioning, with varying effect sizes.
  • Antioxidant vitamins A (beta-carotene) and E (alpha-tocopherol) show promise for elderly cognitive health.
  • Folate, ginkgo biloba, and balanced macronutrient/micronutrient diets may support cognition.

Purpose of the Study:

  • To review the impact of various nutrients and supplements on cognitive function, particularly in the elderly.
  • To assess the efficacy of dietary components and supplements in maintaining or enhancing cognitive performance.
  • To compare the effects of nutritional interventions with medicinal cognition-enhancers.

Main Methods:

  • Literature review of studies on nutrients, supplements, and cognitive performance.

Related Experiment Videos

  • Analysis of research on beta-carotene, alpha-tocopherol, folate, vitamin B12, ginkgo biloba, glucose, and caffeine.
  • Examination of dietary composition effects on elderly cognition.

    • Main Results:

    • Supplementation with beta-carotene and alpha-tocopherol appears beneficial for elderly cognitive function.
    • Folate shows a stronger association with cognitive functioning than vitamin B12.
    • Ginkgo biloba extract can enhance cognitive performance and delay dementia-related decline.
    • A balanced diet rich in micronutrients supports cognitive maintenance in the elderly.
    • Glucose and low-dose caffeine can enhance cognition, though studies often exclude the elderly.

    Conclusions:

    • Nutritional interventions, including specific vitamin supplements and dietary patterns, offer modest benefits for cognitive function in the elderly.
    • The cognitive-enhancing effects of nutritional supplements are comparable to those of some medicinal or investigational drugs.
    • Further research, particularly in elderly populations, is needed for glucose and caffeine effects.