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Maxillary sinusitis mimicking malignant disease.

J F Towers, P G McAndrew

    Oral Surgery, Oral Medicine, and Oral Pathology
    |May 1, 1975
    PubMed
    Summary

    Maxillary sinusitis can mimic neoplastic disease, presenting with bone destruction and unilateral epistaxis. Biopsy is crucial for definitive diagnosis when radiographic signs are ambiguous.

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    Area of Science:

    • Otolaryngology
    • Radiology
    • Pathology

    Background:

    • Differentiating maxillary sinusitis from neoplastic disease is critical for appropriate patient management.
    • Clinical and radiographic findings can sometimes be misleading in distinguishing these conditions.

    Purpose of the Study:

    • To describe the diagnostic features of maxillary sinusitis and neoplastic disease of the maxillary sinus.
    • To highlight the importance of biopsy in cases with ambiguous diagnostic evidence.

    Main Methods:

    • Review of clinical and radiographic presentations of maxillary sinusitis and neoplastic disease.
    • Histologic examination of biopsy specimens for definitive diagnosis.

    Main Results:

    • In most cases, clinical and radiographic evidence accurately differentiates maxillary sinusitis from neoplastic disease.
    • Two presented cases showed radiographic evidence of bone destruction suggestive of neoplasm, but biopsy confirmed sinusitis.
    • Radiographic bone destruction of antral walls can occur in maxillary sinusitis.

    Conclusions:

    • Unilateral epistaxis combined with radiographic bone destruction of the antral walls should raise suspicion for neoplastic disease.
    • Biopsy is essential for definitive diagnosis when there is any doubt between maxillary sinusitis and neoplastic disease.

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