Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The metastatic process: basic research and clinical implications.

A F Chambers1

  • 1London Regional Cancer Centre, and Department of Oncology, University of Western Ontario, London, Canada. ann.chambers@lrcc.on.ca

Oncology Research
|November 24, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin.

Oral surgery, oral medicine, oral pathology and oral radiology·2014
Same author

Palm oil tocotrienols and plant flavonoids act synergistically with each other and with Tamoxifen in inhibiting proliferation and growth of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells in culture.

Asia Pacific journal of clinical nutrition·2014
Same author

Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma.

Oral surgery, oral medicine, oral pathology and oral radiology·2013
Same author

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response.

British journal of cancer·2012
Same author

Removal of a titanium ring using a dental saw.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2012
Same author

Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases.

Physics in medicine and biology·2006
Same journal

New Paradigm in Ocular Surface Squamous Neoplasia-Insights from a Case Report on the Use of Interferon in Treatment.

Oncology research·2026
Same journal

Clinical Application Progress of Artificial Intelligence in Pancreatic Cancer: From Diagnosis to Immunotherapy.

Oncology research·2026
Same journal

Exploring the Role of CD44 in the Progression and Invasion of Chondrosarcoma.

Oncology research·2026
Same journal

Retraction: Long Noncoding RNA Taurine-Upregulated Gene 1 Promotes Cell Proliferation and Invasion in Gastric Cancer via Negatively Modulating miRNA-145-5p.

Oncology research·2026
Same journal

Retraction: Knockdown of Cyclin-Dependent Kinase Inhibitor 3 Inhibits Proliferation and Invasion in Human Gastric Cancer Cells.

Oncology research·2026
Same journal

Targeting Dynamin-Related Protein 1 and Glucose Metabolism Reverses Acquired Resistance to Sorafenib in Liver Cancer.

Oncology research·2026
See all related articles

Understanding cancer metastasis is key to reducing cancer deaths. New insights from in vivo videomicroscopy reveal metastatic inefficiency, offering potential for novel antimetastatic therapies and improved cancer survival rates.

Area of Science:

  • Oncology
  • Cancer Biology
  • Translational Research

Background:

  • Metastasis is the primary cause of cancer-related mortality.
  • Effective antimetastatic therapies require a deep understanding of the metastatic process.
  • Recent advances in in vivo imaging offer new perspectives on metastasis.

Purpose of the Study:

  • To analyze recent experimental findings on cancer metastasis using in vivo videomicroscopy.
  • To evaluate the clinical relevance and implications of these findings for human cancers.
  • To discuss potential impacts on antimetastatic therapy development and cancer patient outcomes.

Main Methods:

  • In vivo videomicroscopy for direct observation and quantification of metastatic steps.
  • Review and contextualization of experimental metastasis findings within human cancer.

Related Experiment Videos

  • Discussion of implications for clinical cancer treatment and patient survival.

    • Main Results:

    • In vivo videomicroscopy has provided novel insights into the inefficiencies of the metastatic process.
    • Experimental findings highlight specific steps contributing to metastatic inefficiency.
    • The relevance of these findings to human cancer metastasis requires further clinical evaluation.

    Conclusions:

    • Experimental insights into metastasis could inform the development of targeted antimetastatic therapies.
    • Understanding metastatic inefficiency may lead to strategies to improve patient survival.
    • Further research is needed to translate these findings into effective clinical interventions for cancer patients.